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The alpha-2 adrenergic receptor antagonist, yohimbine, can facilitate fear extinction in animals and humans. One potential mechanism is increased noradrenergic activity and associated arousal in the presence of conditioned stimuli. Accordingly, yohimbine might augment prolonged exposure (PE) therapy for posttraumatic stress disorder (PTSD), where heightened exposure-oriented arousal is a theorized …

Patients’ words reflect their depression and anxiety We express ourselves in words, intentionally as well as unintentionally, and verbal behavior is influenced by emotional, cognitive and personality factors. Furthermore, words are the essential medium of psychotherapy. Up till now, language has mainly been investigated qualitatively, however, progress in the field …

Early Maladaptive Schemas are best organized into four domains related to their unique history The clinical concept of “schema” was originally utilized by Aaron T. Beck in order to explain underlying mechanisms of emotional disorders. During the 1980s, Jeffrey E. Young further developed the schema concept with particular inspiration from …

Mixed anxiety and depression is common among older adults. The aim of the study was to compare the effects of an eight-week-long tailored internet-supported cognitive behaviour therapy (ICBT) programme and to compare against the provision of weekly general support. A second aim was to investigate if pre-treatment cognitive flexibility and …

60% of patients with depression are attended in the Spanish Primary Care. Nevertheless, half of them, approximately, show low adherence to medication and psychotherapy presents difficulties in delivering interventions to the community because the lack of time and specialized resources. For these reasons, online interventions offer a valuable alternative to …

Hearing loss is extremely common, and not only among older persons. People with hearing loss may experience low quality of life and increased levels of anxiety and depression. This has been found in several studies, and although far from everyone with hearing problems are affected, there certainly are those that …

Depression and anxiety are common conditions, whose symptoms can cause anything from mild discomfort to severe impairment. There is now a substantial evidence base showing the effectiveness of internet-delivered psychological treatments, such as internet-delivered Cognitive Behaviour Therapy (iCBT), for treating the symptoms of depression and anxiety. It is encouraging to …

Intense and prolonged sadness is a defining feature of major depressive disorder (MDD). People with MDD often have difficulty changing their feelings of sadness or lessening the intensity of their emotions. Recalling positive memories can help people without depression to cope with sadness and improve their mood.  However, previous research …

Intolerance of uncertainty, also termed fear of the unknown, may be an important tool to address in therapy. The present study tested for diagnostic differences in two forms of intolerance of uncertainty and examined if changes in the forms of intolerance of uncertainty contribute to improved treatment outcomes. Participants were …

Many of us will experience feeling burdensome to others at some point in our lifetime. Individuals who perceive themselves as burdensome often feel that they fail to contribute to others (e.g., their family, society), and that the world would be better off if they were gone. Feeling burdensome is related …